Catheter ablation therapy for persistent atrial fibrillation typically includes pulmonary vein isolation and may include additional lesions that target patient-specific anatomical, electrical or structural features. We aim to compare ablation techniques across virtual cohorts of atrial fibrillation patients to predict patient-specific outcome and design optimal ablation approaches.
Further reading:
[1] Subject-Specific Ablation of Pathologic Conduction Patterns Beyond the Pulmonary Veins: A Personalised Modelling Approach
[2] Novel Radiofrequency Ablation Strategies for Terminating Atrial Fibrillation in the Left Atrium: A Simulation Study
[3] Patient-specific simulations predict efficacy of ablation of interatrial connections for treatment of persistent atrial fibrillation
[4] Left atrial effective conducting size predicts atrial fibrillation vulnerability in persistent but not paroxysmal atrial fibrillation
[5] Variability in pulmonary vein electrophysiology and fibrosis determines arrhythmia susceptibility and dynamics
[6] In silico comparison of left atrial ablation techniques that target the anatomical, structural and electrical substrates of atrial fibrillation